changes in obsessive compulsive symptoms during manic episodes: a case series

objective: although there are some reports of reduction of obsessive-compulsive symptoms in manic episodes or its exacerbation during depressive episodes, this relationship has not been proved. method: clinical observations of six cases with co-morbidity of bipolar-i-disorder and obsessive-compulsive disorder or symptoms. results: the cases presented here show heterogeneity and variety of the relationships between the obsessions and bipolar-i-disorder.limitations: low sample size and non-random sampling. conclusions: this variety of clinical presentations may indicate the presence of different clinical groups that their validity should be assessed through more systematized studies.